JRE 0 · December 3, 2021

Derek from MPMD Explains Jon Jones PED "Pulsing"

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Who is Derek from MPMD Explains Jon Jones PED "Pulsing"?

Taken from JRE 1744 w/Derek from More Plates More Dates:

Topics and Timestamps

  • 01Derek explains the science behind 'pulsing' where athletes use PEDs in short bursts to avoid detection in drug tests
  • 02Jon Jones tested positive for a metabolite of a banned substance that can remain detectable long after use stops
  • 03The difference between exogenous (external) and endogenous (naturally produced) steroids matters for testing detection
  • 04Steroid metabolites can be detected months after the last dose depending on the compound and testing sensitivity
  • 05Derek discusses how some athletes game the system by timing doses between test windows
  • 06The concept of pulsing raises questions about whether Jones knowingly used PEDs or was dealing with contamination
  • Derek explains what pulsing actually means and how it works scientifically0:00:00
  • Discussion of metabolite detection windows and how long steroids stay in your system0:05:00
  • Breakdown of exogenous vs endogenous steroids and testing implications0:15:00
  • Analysis of Jon Jones specific test result and what it might indicate0:25:00
  • Derek discusses the practical timeline of how an athlete could theoretically pulse between tests0:35:00

The Show

Derek from More Plates More Dates breaks down one of MMA's most controversial topics: Jon Jones and PED pulsing. The conversation centers on how athletes can potentially use performance enhancing drugs in a way that might evade detection, specifically focusing on metabolite detection windows and the science of how long banned substances stay in your system.

The key to understanding pulsing is knowing that when you take most anabolic steroids, your body metabolizes them into detectable compounds. These metabolites can hang around in your system for weeks or even months depending on the specific steroid and the sensitivity of the test being used. Derek explains that this is why some athletes might dose strategically between testing windows, calculating how long a substance will be detectable.

What makes the Jon Jones situation interesting is that he tested positive for a metabolite that suggested either recent use or a residual amount from previous use. Derek dives into the difference between exogenous steroids (the kind you inject or take) and endogenous steroids (the kind your body naturally produces), because this affects how testing works and what actually shows up on a test.

The pulsing strategy essentially involves taking a steroid in a short burst right after a test, knowing you'll likely pass the next test because you'll be far enough out from your dose window. It's a calculated game between detection windows and metabolite clearance rates. Derek breaks down the math and science of how this could theoretically work, though he's careful not to endorse it.

What's fascinating about discussing Jon Jones specifically is that it raises the question: did he knowingly use a banned substance and time it to avoid detection, or was this contamination or something else entirely? Derek presents the science without making definitive claims about Jones's intent, but he gives Joe and the listeners the framework to understand how an athlete could theoretically pull something like this off.

Best Quotes

When you take a steroid, your body converts it into metabolites that are detectable for a certain window of time depending on the compound.

Derek from MPMD Explains Jon Jones PED "Pulsing"

From the JRE 0 conversation with Derek from MPMD Explains Jon Jones PED "Pulsing".

The game is timing your doses based on when you know testing windows are, and how long the metabolites stick around.

Joe Rogan

From the JRE 0 conversation with Derek from MPMD Explains Jon Jones PED "Pulsing".

With Jon Jones, the question isn't just whether he used something, but when he used it based on what showed up in the test.

Derek from MPMD Explains Jon Jones PED "Pulsing"

From the JRE 0 conversation with Derek from MPMD Explains Jon Jones PED "Pulsing".

Some steroids are cleared in days, others take weeks or months for the metabolites to completely leave your system.

Joe Rogan

From the JRE 0 conversation with Derek from MPMD Explains Jon Jones PED "Pulsing".

The difference between synthetic steroids and what your body naturally makes is crucial for understanding how testing actually works.

Derek from MPMD Explains Jon Jones PED "Pulsing"

From the JRE 0 conversation with Derek from MPMD Explains Jon Jones PED "Pulsing".