Mark Sisson on Achieving Metabolic Flexibility Through Fasting

Mark Sisson is a former elite endurance athlete and bestselling author who has become one of the leading voices in metabolic health and ancestral living practices. He founded the Primal Blueprint movement and has spent decades researching how fasting and low-carb nutrition can help people achieve metabolic flexibility, the body's ability to efficiently switch between burning fat and carbohydrates for fuel. Joe brought him on JRE 1624 to dive deep into the science behind these health concepts and explore the philosophical implications of how modern humans can optimize their biology through lifestyle changes. His practical approach to wellness bridges rigorous science with real-world application, making complex metabolic concepts accessible to mainstream audiences.